Assuming her appointment will be confirmed, talk turns to a replacement for her seat in the U.S. Senate.
The task of choosing a successor falls to David Paterson, New York's Democratic governor.
Whomever he picks would serve for two years, before a special election in November 2010 to decide who fills the last two years of Clinton's term.
Paterson has a strong bench to choose from.
There are a number of contenders, including at least eight members of New York's delegation in the House of Representatives, New York State Attorney General Andrew Cuomo, Buffalo Mayor Byron Brown, Bronx Borough President Adolfo Carrion, Nassau County Executive Thomas Suozzi, Caroline Kennedy, and her cousin, Robert Kennedy Jr.
Bill Clinton (pictured) is also among those mentioned to replace Hillary Clinton.
If that happens Bill would be the third former president to go from the White House to Capitol Hill.
President John Quincy Adams lost his re-election bid in 1828. Two years later he returned to Washington after winning election as a congressman from his home state of Massachusetts. He served in the House of Representatives until his death in 1848.
President Andrew Johnson also served as a Senator from Tennessee in 1875, 7 years after the Senate acquitted him of impeachment charges. He died a few months after taking office.
A picture of my cave
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